Philadelphia Phillies vs Los Angeles Dodgers Picks and Prediction for Tuesday September 16 2025

By: Kim Smith Published 09/16/2025, 12:05 AM ET

Two National League heavyweights collide under the lights at Dodger Stadium as the Philadelphia Phillies (89–61) visit the Los Angeles Dodgers (84–65) in a potential postseason preview. With both teams pushing for playoff seeding, this matchup showcases star power on both the mound and at the plate. First pitch is set for 10:10 PM ET on Tuesday, September 16, 2025, airing nationally on TBS. Don’t miss the breakdown and betting edges in our free MLB picks.

Game Information

  • Date: Tuesday, September 16, 2025

  • Time: 10:10 PM ET

  • Venue: Dodger Stadium, Los Angeles, CA

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  • Broadcast: TBS

  • Weather: Clear skies, 81°F at first pitch

Team Form & Recent Results

Philadelphia Phillies The Phillies remain one of the NL’s hottest teams, sitting at 89–61 despite dropping their last game to Kansas City. They’ve won 3 of their last 5, powered by an explosive offense led by Kyle Schwarber’s league-best 52 home runs. Their lineup continues to mash, scoring 33 runs over that stretch.

Los Angeles Dodgers The Dodgers come in at 84–65 and are red-hot, winning 4 of their last 5 including back-to-back blowouts of San Francisco. Their offense has been relentless, tallying 32 runs across the last three games. With one of MLB’s best home records (48–26), they’re tough to beat at Dodger Stadium.

Pitching Matchup

Philadelphia – Cristopher Sanchez (LHP) Sanchez has quietly been dominant, posting a 13–5 record with a 2.57 ERA and 1.11 WHIP across 182.1 innings. His 192 strikeouts highlight his ability to miss bats, and he enters this game as the Phillies’ most consistent starter down the stretch.

Los Angeles – Shohei Ohtani (RHP) Ohtani brings dual-threat star power but will take the mound here, looking to build on a solid 3.75 ERA and 49 strikeouts in 36 innings. Still easing back into a starter’s rhythm, he faces one of the toughest lineups in baseball but has shown flashes of dominance with his electric fastball-splitter combo.

Standout Players and Key Injuries

  • Phillies: Kyle Schwarber (52 HR, 127 RBI) is a game-changer at the plate, while Trea Turner (.305 AVG) adds consistency—though Turner is currently on the 10-day IL.

  • Dodgers: Ohtani leads the team with 49 homers and 93 RBI, supported by Freddie Freeman (.296 AVG). Catcher depth is thin with Will Smith on the IL.

  • Injuries: Phillies remain without Alec Bohm and Turner for the short term. Dodgers’ catching situation is a concern with both Dalton Rushing and Smith sidelined.

Betting Odds & Market Overview

  • Moneyline: Phillies +105 | Dodgers -125

  • Run Line: Phillies +1.5 (-165) | Dodgers -1.5 (+140)

  • Total: Over/Under 8.5 (O -115 / U -105)

The Dodgers opened as slight favorites due to home-field advantage and Ohtani’s presence on the mound. However, public money has been fairly balanced, reflecting confidence in Sanchez’s strong season.

Picks & Predictions

  • Phillies ML (+105): Sanchez gives Philadelphia an edge in the pitching matchup.

  • Over 8.5 (-115): Both lineups are capable of big innings, especially in a hitter-friendly park.

  • Final Score Projection: Phillies 6, Dodgers 4

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